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產(chǎn)品中心抗體Polyclonal AntibodyK106679PAnti-CASP8 Polyclonal Antibody
產(chǎn)品型號：K106679P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：958
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產(chǎn)品分類
Anti-CASP8 Polyclonal Antibody
| 英文名稱 | Anti-CASP8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | ALPS2B;CAP4;Casp-8;FLICE;MACH;MCH5 |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反應(yīng) | Human |
| 蛋白分子量 | 55kDa |
| Gene ID | 841 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human CASP8 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human CASP8 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q14790 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. |
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